Learn about Letrozole, an aromatase inhibitor used to treat hormone-receptor positive breast cancer in postmenopausal women. Uses, safety, and precautions.
What Letrozole Is and How It Is Used
What Letrozole Is and How It Works
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Letrozole contains the active ingredient letrozole and belongs to a class of medications known as aromatase inhibitors. It is a hormonal (endocrine) therapy primarily used in the treatment of breast cancer.
Certain types of breast cancer grow in response to oestrogen, a female sex hormone. Letrozole works by blocking the aromatase enzyme, which is responsible for producing oestrogen in the body. By lowering oestrogen levels, letrozole can help slow or stop the growth and spread of hormone-dependent breast cancer cells.
What Letrozole Is Used For
Letrozole is prescribed for the treatment of breast cancer in women who are postmenopausal (have stopped having menstrual periods).
It may be used:
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To reduce the risk of cancer recurrence
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As an initial treatment when surgery is not immediately appropriate
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After breast cancer surgery
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Following five years of tamoxifen therapy
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To help prevent the spread of advanced breast cancer to other areas of the body
If you have questions about how letrozole works or why it has been prescribed, consult your healthcare provider.
What You Should Know Before Taking Letrozole
Always follow your doctor’s instructions carefully, as they may differ from the general guidance provided here.
Do Not Take Letrozole If:
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You are allergic to letrozole or any of the other ingredients in the product
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You are still menstruating and have not reached menopause
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You are pregnant
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You are breastfeeding
If any of these apply to you, do not take letrozole and speak with your doctor.
Warnings and Precautions
Consult your doctor or pharmacist before starting letrozole to ensure it is appropriate for your medical condition.
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